Outpatient: 25-50 mg PO qHS initially; increase by 25 mg every 5-7 days to 100-200 mg/day (may divide doses throughout day or give at bedtime); if needed, may increase to 300 mg/day 600 medications are known to interact with prednisone. It has anticholinergic and sedative properties Label. It can be dangerous to take amitriptyline with: Nov 2, 2023 · Amitriptyline can cause drug interactions and side effects, some of them severe. Continue to take amitriptyline even if you feel well. Arrhythmias, heart block. In this case, skip the missed dose and take your next dose at the usual time. You might start to feel better within a few weeks. The use of tricyclic and tetracyclic antidepressants to treat depression began with reports in 1958 that imipramine was particularly effective for melancholic depression, marked by symptoms such as psychomotor retardation, anergia, dysphoria, hopelessness, and diurnal variation []. Methadone and other opiates (for example, heroin) can increase the risk of severe drowsiness if you're taking amitriptyline. Amitriptyline has been shown to cross the placenta. Do not stop taking Amitriptyline after 1 or 2 weeks just because you feel it is not helping your symptoms. If you are due to have any medical treatment, tell the person carrying out the treatment that you are taking amitriptyline as it can interfere with some anaesthetics. If vomiting occurs when given on an empty stomach, try giving future doses with food or a treat. Topiramate may raise amitriptyline levels in the body. It's best to take amitriptyline in the evening or before you go to bed. It is important to be aware of these risks when taking amitriptyline. Jan 8, 2024 · Nortriptyline and amitriptyline are orally administered tricyclic antidepressants (TCAs) used to treat major depressive disorder (MDD) or, in an off-label setting, nerve pain or migraine prevention. Adults. Amitriptyline, doxepin, and imipramine have been associated with more weight gain than some other TCAs; nortriptyline and desipramine may be better tolerated. Also describe any vitamins, herbs, or Nov 2, 2023 · Amitriptyline can cause drug interactions and side effects, some of them severe. Symptoms of overdosage may include dry mouth, coma of varying degree, hypotension, hypothermia, hyperreflexia, extensor plantar responses, convulsions, respiratory failure, cardiac conduction defects, and arrhythmias. It works in the central nervous system (CNS) to elevate the mood of people with depression. Talk to your GP if you're thinking of stopping taking amitriptyline. people take it for many months, even years, without having any negative effects. 2 (3. Amitriptyline can cause mild and transient serum enzyme elevations and is rare cause of clinically apparent acute cholestatic liver injury. It comes Aug 1, 2024 · Taking amitriptyline together with medicines used during surgery may increase the risk of side effects. You can take the tablets with or without food. 8) and the number needed to treat for an additional harmful outcome was 5. Adolescents ages 13 to 17 can also take amitriptyline, but will likely start at a lower dose. The starting amitriptyline dosage is usually 50 mg to 100 mg per day. Apr 17, 2023 · For example, amitriptyline, doxepin, imipramine and trimipramine are more likely to cause sedation than nortriptyline and desipramine. Effects in pain and depression. It may be used off-label to treat other conditions such as chronic pain, fibromyalgia, or insomnia. Most people can take amitriptyline. Oct 24, 2022 · Amitriptyline is most commonly prescribed in tablet form, with tablet strengths ranging from 10 mg to 150 mg. Nov 20, 2022 · You should not take amitriptyline while taking an MAOI and for at least 14 days after stopping the MAOI. Prescribe amitriptyline with caution to people with: A history of bipolar disorder or psychosis. 87. Although not all of these side effects may occur, if they do occur they may need medical attention. w/ incr. Some antidepressants can affect the way amitriptyline works and can cause very high blood pressure. Midodrine Interactions. Jul 31, 2023 · In the treatment of depression, you should feel some relief from amitriptyline in 2 to 4 weeks, but it may take up to 8 to 12 weeks to feel the full therapeutic effects. In addition, from time to time, he engaged in binge ingestion of amitriptyline when he wanted to experience a “high” in his mood. Recent myocardial infarction. 600 medications are known to interact with prednisone. Overdosage with amitriptyline is associated with a relatively high rate of fatality. incr. It is created by eHealthMe based on reports of 1,333 people who take the same drugs from the FDA, and is updated regularly. Generic amitriptyline is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower. Amitriptyline HCl is supplied as 10 mg, 25 mg, 50 mg, 75 mg, 100 mg or 150 mg tablets. 10mg; 25mg; 50mg; 75mg; 100mg; 150mg; Depression. Never take 2 Mar 1, 2016 · Amitriptyline is a tricyclic antidepressant that is widely used in the therapy of depression. However, the amitriptyline dosage for sleep generally starts at 10 mg. benefit; in short-term studies of antidepressants vs. But you should speak to your doctor before taking amitriptyline if you: • have ever had an allergic reaction to amitriptyline or any other medicine 600 medications are known to interact with prednisone. Missed dose: If you forget to take your dose, take it as soon as you remember that day. S. It may take a few weeks or longer before you feel the full benefit of amitriptyline. This can happen even after you stop taking them. Taking these drugs together (or within 14 days of each other) may cause serious side Oct 3, 2023 · Amitriptyline is an effective antidepressant but it may cause drowsiness initially and a withdrawal syndrome with abrupt discontinuation. For oral dosage forms (tablets): For depression: If a TCA is needed, amitriptyline is one of the preferred agents. But you should speak to your doctor before taking amitriptyline if you: have ever had an allergic reaction to amitriptyline or any other medicine; have a heart problem – amitriptyline can make some heart problems worse; have liver or kidney problems The phase IV clinical study analyzes what interactions people have when they take Prednisone and Amitriptyline hydrochloride. See full list on ehealthme. Key facts. Mar 11, 2024 · Taking prednisone alongside immunosuppressants, such as chemotherapy, certain biologics, or biosimilars, can make it harder to fight off infections. It also has the ability to deal with Nov 2, 2023 · Amitriptyline can cause drug interactions and side effects, some of them severe. Many people stop taking the medicine because they experience side effects early on but do not feel any benefit. You may start to feel better after 1 or 2 weeks, but it can take 6 weeks for amitriptyline to work as a painkiller. Keep taking it! You may notice pain relief as quickly as two weeks after starting, but often amitriptyline requires to be taken for six to eight weeks at the optimal dose level before one can say the drug has been given a fair trial. Take amitriptyline in the evening or before you go to bed, because it can make you feel sleepy. Migraine prophylaxis should be avoided during pregnancy; if needed, amitriptyline may be used if other agents are ineffective or contraindicated (Pringsheim 2012). You can take amitriptyline with or without food. Check with your doctor immediately if any of the following side effects occur while taking amitriptyline: Incidence not known Take this medication by mouth with a drink of water. Tell your doctor if you've ever taken any medicines for depression. It is more popular than comparable drugs. The phase IV clinical study analyzes what interactions people have when they take Prednisone and Amitriptyline hydrochloride. Apr 21, 2023 · Amitriptyline is an tricyclic antidepressants (TCA) and is used to treat depression. This is because it can make you feel sleepy. Initially 10–25 mg daily, dose to be taken in the evening, then increased, if tolerated, in steps of 10–25 mg every 3–7 days in 1–2 divided doses; usual dose 25–75 mg daily, dose to be taken in the evening, doses above 100 mg should be used with caution (doses above 75 mg should be used with caution in the elderly and in patients with The phase IV clinical study analyzes what interactions people have when they take Prednisone and Amitriptyline hydrochloride. Feb 16, 2021 · If you stop taking the drug or don’t take it at all: If you don’t take this drug, your depression and anxiety may get worse. If you stop taking this drug suddenly, you may have withdrawal Amitriptyline for pain and migraine Find out how amitriptyline treats pain and prevents migraine and how to take it. Your healthcare provider may raise your amitriptyline dose over time based on your response. Find patient medical information for amitriptyline oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. But, if it is Find patient medical information for Sk-Amitriptyline oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. This means the common side effects tend to be milder and go away within a few days. Sometimes it is not safe to use certain medications at the same Suicidality. How long does Amitriptyline take to work? You may see an improvement in your symptoms after a couple of weeks, although it usually takes between 4 and 6 weeks before you feel the benefits. Continue to take amitriptyline unless your doctor tells you Mar 8, 2024 · What other drugs will affect amitriptyline? Taking amitriptyline with other drugs that make you sleepy can worsen this effect. Give the medicine at least 6 weeks to work. Here's what I did to document such occurrences: Take notes: I made detailed notes about any side effects or allergic reactions, including the specific symptoms, their severity, and the timing of occurrence. To lower your risk for weight gain while taking amitriptyline, make sure to eat a healthy diet and follow a regular exercise routine. Doses of amitriptyline for pain are lower than the doses for depression. If you experience changes to your heart rate while taking amitriptyline, contact your prescriber right away. Safety of amitriptyline in pregnancy has not been established. The non-FDA approved indications are anxiety, post-traumatic … Mar 22, 2024 · Patients should be advised that taking amitriptyline hydrochloride tablets can cause mild pupillary dilation, which in susceptible individuals, can lead to an episode of angle-closure glaucoma. Documenting any side effects or allergic reactions experienced while taking Amitriptyline is crucial for monitoring and ensuring my safety. A significant risk of suicide. Find everything you need to know about Amitriptyline (Elavil), including what it is used for, warnings, reviews, side effects, and interactions. Maternal serum concentrations should be monitored during pregnancy (Larsen 2015; Yonkers 2009). Follow the directions on the prescription label. You can find detailed information about this drug in the official Patient Information Leaflet (PIL). The risk ratio (RR) was 1. [12] Apr 17, 2023 · Federal Register. Who can take amitriptyline? Most people can take amitriptyline. What do I do if I miss a dose? Nov 2, 2023 · Amitriptyline can cause drug interactions and side effects, some of them severe. This may make amitriptyline side effects more likely, including drowsiness or dizziness. There are 168 drugs known to interact with midodrine, along with 4 disease interactions, and 1 alcohol/food interaction. NP symptom inventory score (NPSI) significantly decreased in all groups Jan 29, 2021 · He could not control taking amitriptyline in excess doses despite its regular side effects, which include constipation. Suicidality Antidepressants may increase risk of suicidal thinking and behavior (suicidality) in children, adolescents, and young adults (18–24 years of age) with major depressive disorder and other psychiatric disorders; balance this risk with clinical need. Before you take a new drug, ask your doctor or pharmacist questions like: Can I take this with my other meds? Should I avoid certain foods, drinks, or other products? Before you take a new drug, ask your doctor or pharmacist questions like: Can I take this with my other meds? Should I avoid certain foods, drinks, or other products? Aug 6, 2023 · Studies show that people gained 1 to 16 pounds while taking amitriptyline. Aug 8, 2022 · Amitriptyline oral tablet is a prescription medication that’s used to treat symptoms of depression. Sep 18, 2023 · Serious side effects of Amitriptyline. placebo, suicidality risk not incr. Oct 3, 2023 · Amitriptyline is an effective antidepressant but it may cause drowsiness initially and a withdrawal syndrome with abrupt discontinuation. Before you take a new drug, ask your doctor or pharmacist questions like: Can I take this with my other meds? Should I avoid certain foods, drinks, or other products? Cannabis with amitriptyline can make you feel very sleepy, especially if you've just started taking the medicine. Read all information given to you. Do not stop taking amitriptyline without talking to your doctor. Amitriptyline may increase the risk of seizures if you have epilepsy or a history of seizures. Amitriptyline, sold under the brand name Elavil among others, is a tricyclic antidepressant primarily used to treat major depressive disorder, and a variety of pain syndromes such as neuropathic pain, fibromyalgia, migraine and tension headaches. Severe hepatic impairment. They’ll be able to give you directions to safely stop the medication over time. amitriptyline. were taking three or more prescription medications. This medicine is a tricyclic antidepressant (TCA). 1) (low quality evidence). These common side effects of amitriptyline happen in more than 1 in 100 people. Serious adverse events were rare. Jun 20, 2024 · Amitriptyline can be used to treat both children and adults, but the AHS and AAN recommend other drugs (like topiramate) that are more likely to be effective in treating kids. If you suddenly stop taking amitriptyline, you may experience withdrawal symptoms such as nausea, headache, and lack of energy. This drug in indicated for the following conditions: Major depressive disorder in adults Management of neuropathic pain in adults Prophylactic treatment of chronic tension-type headache (CTTH) in adults Prophylactic treatment of migraine in adults Treatment of nocturnal enuresis in children aged 6 years and above when organic pathology, including spina bifida and related disorders, have been Mar 11, 2024 · Taking prednisone alongside immunosuppressants, such as chemotherapy, certain biologics, or biosimilars, can make it harder to fight off infections. Mixing amitriptyline with herbal remedies and supplements. Dec 12, 2022 · How is this drug best taken? Use this drug as ordered by your doctor. 5 days vs. The full therapeutic effect may take as long as 30 days to develop. in pts 65 yo and older; depression and certain other psychiatric disorders themselves assoc. Taking amitriptyline for pain will not have the same effect as taking it for depression. This leaflet should come with your medication, usually inside the box. Aggarwal. Cannabis can also make drowsiness worse, especially if you've just started taking amitriptyline. The non-FDA approved indications are anxiety, post-traumatic stress disorder, insomnia, chronic pain (diabetic neuropathy, fibromyalgia), irritable bowel Side Effects. Using them together can also give you a fast heartbeat. Do not take it more often than directed. Amitriptyline Hcl 25mg Tablet is normally taken before bedtime because it can make you feel sleepy. Do not prescribe amitriptyline to people with: Acute porphyria. But it can take 6 weeks for amitriptyline to reduce the amount of pain you feel. But it’s sometimes used off-label for other reasons, such as migraine prevention. Sep 7, 2022 · Q. 1. It is usually taken as a single dose at bedtime, but your dose may be different. Amitriptyline is an FDA-approved medication to treat depression in adults. Swallow your amitriptyline tablets with a glass of water. 5 (95% confidence interval (CI) 1. Taking amitriptyline together with medicines used during surgery may increase the risk of side effects. If you notice a change in the results of your blood or urine sugar tests, or if you have any questions, check with your doctor. Keep taking this drug as you have been told by your doctor or other health care provider, even if you feel well. Dec 11, 2023 · INTRODUCTION. Different doses of this medicine help in treating and preventing different problems such as depression, neuropathic pain, and migraine. Oct 4, 2023 · This is because amitriptyline can alter the levels of sugar in your blood. Sep 16, 2022 · Patients should be advised that taking amitriptyline hydrochloride tablets can cause mild pupillary dilation, which in susceptible individuals, can lead to an episode of angle-closure glaucoma. May 31, 2019 · Amitriptyline is often prescribed for sleep. Feb 22, 2023 · Chances are meloxicam is not the only medication you're taking. Take at bedtime if taking once a day. Amitriptyline may also be specially compounded into a liquid form; make sure to follow the use and storage recommendations on the label. For nerve-related (neuropathic) pain, lower doses of amitriptyline are typically used and it also may take up to 6 weeks to feel the full effects. 18. You shouldn’t stop taking amitriptyline without your prescriber’s OK. It can be dangerous to take amitriptyline with: methadone; stimulants like MDMA (ecstasy) or cocaine; hallucinogens like LSD Mar 11, 2024 · Taking prednisone alongside immunosuppressants, such as chemotherapy, certain biologics, or biosimilars, can make it harder to fight off infections. Jan 1, 2019 · One study demonstrated that patients taking lisinopril reported fewer days with migraines compared with those taking a placebo (14. Determination that Elavil (Amitriptyline Hydrochloride) oral tablets, 10, 25, 50, 75, 100, and 150 milligrams, were not withdrawn from sale for reasons of safety or effectiveness. The amount of weight you might gain can depend on your dose and how long you're taking the medication. But is it safe to take all these medications together? Let’s take a look at seven meloxicam interactions you should be aware of. For patients taking Amitriptyline as a maintenance drug, the usual dosage ranges from 50mg to Cannabis with amitriptyline can give you a fast heartbeat. Aug 11, 2021 · The recommended starting dose of amitriptyline for migraine is 10 milligrams (mg) per day. Tablet. Includes amlodipine, lisinopril, aspirin. Nov 10, 2021 · Patients should be advised that taking amitriptyline hydrochloride tablets can cause mild pupillary dilation, which in susceptible individuals, can lead to an episode of angle-closure glaucoma. Usually, these groups of patients are given 10mg of Amitriptyline (3x a day) and sometimes, the last dosage (bedtime dosage) is increased to 20mg. Learn more about Amitriptyline (Elavil) at Check with your doctor before taking any of the above while you are using this medicine. 3 to 1. Of the total drug interactions, 8 are major, 150 are moderate, and 10 are minor. This includes information on what the medication is for, how to take it, possible side effects and safety information. 24 Studies for Adult and pediatric dosage. Warning. Jan 8, 2024 · Elavil (amitriptyline) is a tricyclic antidepressant that's sometimes prescribed off-label for back pain, neck pain, and migraines. com Oct 17, 2022 · Amitriptyline is a medication approved for depression. Outpatient: 25-50 mg orally every evening initially; increased by 25 mg every 5-7 days to 100-200 mg/day (may divide doses throughout day or give at bedtime); if needed, may increase to 300 mg/day Nov 2, 2023 · Amitriptyline can cause drug interactions and side effects, some of them severe. Apo-Amitriptyline: Amitriptyline belongs to a family of medications known as tricyclic antidepressants. Before you take a new drug, ask your doctor or pharmacist questions like: Can I take this with my other meds? Should I avoid certain foods, drinks, or other products? Dec 16, 2023 · In a clinical study conducted by Chakrabarty and colleagues, the efficacy of pregabalin (150 mg) monotherapy, amitriptyline (25 mg) monotherapy, and low-dose pregabalin (75 mg) plus amitriptyline (10 mg) as combination therapy for reducing NP symptoms was investigated . If you aren’t getting adequate migraine prevention and aren’t having intolerable side effects, your . Bradycardia 600 medications are known to interact with prednisone. Along with its needed effects, amitriptyline may cause some unwanted effects. Ask your doctor before taking amitriptyline with a sleeping pill, narcotic pain medicine, muscle relaxer, or medicine for anxiety, depression, or seizures. suicide risk; observe all Jul 6, 2015 · More participants experienced at least one adverse event; 55% of participants taking amitriptyline and 36% taking placebo. While this is not an FDA-approved use of this medication, doctors may prescribe it for sleep and often do. Pre-existing glaucoma is almost always open-angle glaucoma because angle-closure glaucoma, when diagnosed, can be treated definitively with iridectomy. It is used to treat depression. Before you take a new drug, ask your doctor or pharmacist questions like: Can I take this with my other meds? Should I avoid certain foods, drinks, or other products? Mar 11, 2024 · Taking prednisone alongside immunosuppressants, such as chemotherapy, certain biologics, or biosimilars, can make it harder to fight off infections. This medication can take a few weeks before full effects are noted, but side effects can occur immediately. If you forget to take it. Aug 1, 2024 · Taking amitriptyline together with medicines used during surgery may increase the risk of side effects. It can be taken with or without food. This medicine may affect blood sugar levels. Feb 7, 2020 · For adolescent (10-19 years old) and elderly (60 years old and above) patients, lower dosages are given. Symptoms of manic phase of bipolar disorder. Drug information provided by: Merative, Micromedex® Along with its needed effects, a medicine may cause some unwanted effects. Clinical studies have shown that oral amitriptyline achieves, at a minimum, good to moderate response in up to 2/3 of patients diagnosed with post-herpetic neuralgia and 3/4 of patients diagnosed with diabetic neuropathic pain, and Mar 11, 2024 · Taking prednisone alongside immunosuppressants, such as chemotherapy, certain biologics, or biosimilars, can make it harder to fight off infections. Do not take St John's wort, a herbal remedy often taken for depression The amount of medicine that you take depends on the strength of the medicine. Do not stop taking this medication suddenly except upon the advice of your care team. In such circumstances, the number of tablets even reached to 25-30 per occasion (625–750 mg). You may still be able to take both topiramate and amitriptyline. Amitriptyline is used to treat symptoms of depression. Amitriptyline is used to treat depression. Nov 5, 2022 · Amitriptyline has been shown to cross the placenta. Amitriptyline belongs to a class of drugs called tricyclic antidepressants (TCAs). When you start taking amitriptyline. Depression. There are benefits to taking amitriptyline Apr 21, 2023 · It can also happen if you stop taking amitriptyline suddenly. Pharmacodynamics. It’s safe to be prescribed to adults or children. Take your medication at regular intervals. suicidality risk in children, adolescents, and young adults w/ major depressive or other psychiatric disorders; weigh risk vs. Although a causal relationship has not been established, there have been a few reports of adverse events, including CNS effects, limb deformities, or developmental delay, in infants whose mothers had taken amitriptyline during pregnancy. Medscape - Indication-specific dosing for (amitriptyline, perphenazine), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost information. Amitriptyline may affect your ability to drive or operate heavy machinery. Your doctor will advise you about this. Contact your provider if you're Before you take a new drug, ask your doctor or pharmacist questions like: Can I take this with my other meds? Should I avoid certain foods, drinks, or other products? Oct 3, 2023 · Amitriptyline is an effective antidepressant but it may cause drowsiness initially and a withdrawal syndrome with abrupt discontinuation. If you forget a dose of amitriptyline, take it as soon as you remember, unless it's nearly time for your next dose. Children who take amitriptyline for migraines while also receiving cognitive behavioral therapy may be more likely to benefit from the combined treatment. Aug 29, 2022 · Timing: Take amitriptyline at the same times each day. Side effects of amitriptyline include fast heart rate, blurred vision, urinary retention, dry mouth, constipation, sexual dysfunction, weight gain or loss, and low blood pressure on standing (orthostatic hypotension). Apr 27, 2023 · Amitriptyline HCl, a dibenzocycloheptadiene derivative, has a molecular weight of 313. 6 to 9. Before having any kind of surgery, tell the medical doctor in charge that you are using this medicine. Jul 18, 2023 · Amitriptyline is in the tricyclic antidepressant (TCA) drug classification and acts by blocking the reuptake of both serotonin and norepinephrine neurotransmitters. Maintenance doses should be reduced to the lowest amount that will maintain relief of symptoms when satisfactory improvement has been obtained. 5 days [95% CI, 9 to 34 days]). In fact, between 2015 and 2018, about 24% of people in the U. Follow all instructions closely. “The amitriptyline dose should start at the lower doses of 10 mg to 25 mg for sleep,” says Dr. It is a white, odorless, crystalline compound which is freely soluble in water. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. Amitriptyline should not be taken if you have had a recent heart attack. Nov 2, 2023 · Amitriptyline can cause drug interactions and side effects, some of them severe. in pts >24 yo, and risk decr. May 12, 2023 · Amitriptyline is a tricyclic antidepressant that’s FDA-approved for depression in adults. The Elavil dosage for pain is different than it is for depression, and it may depend on exactly where your pain is, as well. Aspirin and other NSAIDs Before you take a new drug, ask your doctor or pharmacist questions like: Can I take this with my other meds? Should I avoid certain foods, drinks, or other products? Before you take a new drug, ask your doctor or pharmacist questions like: Can I take this with my other meds? Should I avoid certain foods, drinks, or other products? Jul 11, 2024 · Amitriptyline has been shown to cross the placenta. Make sure you tell your healthcare provider about any other medications you are taking and keep them informed if you experience side effects like suicidal thoughts, seizures, or sleep disturbances. Amitriptyline is only available as a generic drug; all brands have been discontinued. Some of the common side effects of amitriptyline gradually improve as your body gets used to the medicine. Feb 19, 2020 · Amitriptyline Hcl 25mg Tablet is a tricyclic antidepressant. Your healthcare professional (HCP) will likely monitor you frequently if you’re taking prednisone along with medications such as these. Amitriptyline is a tricyclic antidepressant and an analgesic. It works on the central nervous system (CNS) to increase levels of certain chemicals in the brain. Some people take it for many months and even for years but it should be reviewed regularly with your doctor. Finally the doctor said she wanted me to try Amitriptyline and I can say that it took maybe about 4 days or so and I really started feeling relief but then, I noticed that the 25 mg stopped working afte r about 2 months and had to go up to the 50 mg which also worked about 2 months and now taking 100 mg. Jun 18, 2021 · Before taking amitriptyline oral tablets, be sure to tell your doctor about all medications you take, including prescription and over-the-counter types. Amitriptyline is a tricyclic antidepressant. While similar, they carry notable differences potential users should understand. khwnjm bkvg dayqo zhbr ezxsb xdsas lqheu kthyp xxmiajk oftwmkecy